Rabeprazole : Uses, Side Effects, Interactions & More
Why is this medication prescribed?
Rabeprazole is used to treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which the backward flow of acid from the stomach causes heartburn and possible injury to the esophagus (the tube that connects the throat and stomach. ) in adults and children over 1 year of age and older. Rabeprazole is used to treat damage from GERD, allow the esophagus to heal, and prevent further damage to the esophagus in adults. Rabeprazole is also used to treat conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome in adults. Rabeprazole is used to treat ulcers (sores in the lining of the stomach or intestine) and is used in combination with other medications to kill H. pylori, a bacteria that causes ulcers in adults. Rabeprazole belongs to a class of medications called proton pump inhibitors. It works by decreasing the amount of acid produced in the stomach.
How should this medicine be used?
Rabeprazole comes as a delayed-release tablet (releases the medication in the intestine to prevent decomposition of the medication by stomach acids) and a delayed-release dusting capsule (capsule containing small granules of medication that are sprayed on food or liquids) take orally. Delayed-release tablets are generally taken once a day. When used to treat ulcers, rabeprazole tablets are taken after the morning meal. When used in combination with other medicines to remove H. pylori, rabeprazole tablets are taken twice a day, with morning and afternoon meals, for 7 days. Rabeprazole dusting capsules are generally taken once a day 30 minutes before a meal. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take rabeprazole exactly as directed. Do not take more or less or take it more often or for a longer period of time than prescribed by your doctor.
Swallow the tablets whole with water; do not break, chew, or crush them.
To take the sprinkle capsules, open one capsule and sprinkle the granules on a small amount of fresh soft food such as applesauce, fruit or vegetable baby food, or yogurt and swallow the mixture immediately (within 15 minutes) without chew or crush the granules. You can also open a capsule and pour the contents into a small amount of cold liquid, such as infant formula, apple juice, or pediatric electrolyte solution, and swallow the mixture immediately (within 15 minutes) without chewing or crushing the granules.
Continue to take rabeprazole even if you feel well. Do not stop taking rabeprazole without talking to your doctor. If your condition does not improve or if it worsens, call your doctor.
Other uses for this medicine
This medication may be prescribed for other uses; Ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking rabeprazole,
• Tell your doctor and pharmacist if you are allergic to rabeprazole, dexlansoprazole (Dexilant), esomeprazole (Nexium), lansoprazole (Prevacid, in Previpac), omeprazole (Prilosec, in Zegerid), pantoprazole (Protonix), any other medications , to any other medicine, The ingredients in rabeprazole tablets or in sprinkled capsules. Ask your pharmacist for a list of the ingredients.
• Tell your doctor if you are taking rilpivirine (Edurant, in Complera, Odefsey). Your doctor will probably tell you not to take rabeprazole if you are taking this medicine.
• Tell your doctor and pharmacist what prescription and over-the-counter medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: certain antibiotics, anticoagulants (‘blood thinners’) such as warfarin (Coumadin), atazanavir (Reyataz), cyclosporine (Neoral, Sandimmune), dasatinib (Sprycel), digoxin (Lanoxin), diuretics ( ‘water pills’), erlotinib (Tarceva), itraconazole (Onmel, Sporonox), ketoconazole (Nizoral), iron supplements, methotrexate (Trexall, Xatmep), mycophenolate mofetil (Cellcept), nelfinavir (Viracept), nilotinib (Tasigna) , saquina (Invirase) and tacrolimus (Prograf). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
• Tell your doctor if you have or have ever had a low level of magnesium in your blood, low levels of vitamin B-12 in your body, osteoporosis, an autoimmune disease (condition in which the body attacks its own organs, causing swelling. and loss of function) such as systemic lupus erythematosus or liver disease.
• Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking rabeprazole, call your doctor.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed dose.
What side effects can this medication cause?
Rabeprazole may cause side effects. Tell your doctor if these symptoms are severe or do not go away:
- sore throat
Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately, or get emergency medical help:
- blistering or peeling skin
- muscle spasms, , cramps, or weakness
- uncontrollable shaking of a part of the body
- rash on cheeks or arms that is sensitive to sunlight
- decreased urination
- blood in the urine
- severe diarrhea with watery stools, stomach pain, or fever that does not go away
- new worsening joint pain
- swelling of the eyes, face, mouth, lips, tongue, or throat
- difficulty breathing or swallowing
- irregular, fast, or pounding heartbeat
- excessive tiredness
Rabeprazole may cause other side effects. Call your doctor if you have any unusual problems while taking this medicine.
People who take proton pump inhibitors like rabeprazole may be more likely to fracture their wrists, hips, or spine than people who don’t take one of these drugs. People who take proton pump inhibitors can also develop fundic gland polis (a type of growth in the lining of the stomach). These risks are highest in people who take high doses of one of these medications or take them for a year or more. Talk to your doctor about the risk of taking rabeprazole.
If you experience a serious side effect, you or your doctor can submit an online report to the Food and Drug Administration (FDA) MedWatch Adverse Event Reporting Program (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about storage and disposal of this medication?
Keep this medicine in its container, tightly closed and out of the reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
It is important to keep all medications out of the sight and reach of children, as many containers (such as those for taking pills weekly and those used for eye drops, creams, patches, and inhalers) are not resistant to children and children. young children can easily open them. To protect young children from poisoning, always close the safety caps and immediately put the medicine in a safe place, one that is above and out of your sight and reach. http://www.upandaway.org
Unnecessary medications must be disposed of in special ways to ensure that pets, children, and others cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to get rid of your medication is through a medication take-back program. Talk to your pharmacist or contact your local garbage / recycling department for information on return programs in your community. Check out the FDA’s Safe Drug Disposal website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
In case of emergency/overdose
In case of overdose, call the Poison Control Helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim collapsed, had a seizure, is having trouble breathing, or cannot wake up, call 911 immediately.
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor may order certain laboratory tests before and during your treatment, especially if you have severe diarrhea.
Before having a laboratory test, tell your doctor and the laboratory personnel that you are taking rabeprazole.
Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription.
It is important that you keep a written list of all prescription and over-the-counter (non-prescription) medications you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should carry this list with you every time you visit a doctor or if you are admitted to a hospital. It is also important information to take with you in emergencies.
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