Midamor : Uses, Side Effects, Interactions & More

Why is this medication prescribed?

Midamor (Amiloride) is generally used in combination with other diuretics (‘water pills’) to treat high blood pressure and heart failure in patients who have low amounts of potassium in the body or for whom low levels of potassium in the body could be dangerous. Midamor (Amiloride) is in a class of medications called diuretics. It works by causing the kidneys to remove unnecessary water and salt from the body into the urine, but it reduces the loss of potassium.

High blood pressure is a common condition, and when left untreated it can damage the brain, heart, blood vessels, kidneys, and other parts of the body. Damage to these organs can cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medications, making lifestyle changes will also help control your blood pressure. These changes include eating a diet low in fat and salt, maintaining a healthy weight, exercising for at least 30 minutes most days, not smoking, and consuming alcohol in moderation.

How should this medicine be used?

Midamor (Amiloride) comes as a tablet to take by mouth. It is usually taken once a day with food. To remind you to take Midamor, take it at around the same time every day. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any parts you do not understand. Take Midamor exactly as directed. Do not take more or less, or take it more often than prescribed by your doctor.

This drug controls high blood pressure and heart failure, but it does not cure these conditions. Keep taking Midamor even if you feel fine. Do not stop taking Midamor without consulting your doctor.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking Midamor,

  • Tell your doctor and pharmacist if you are allergic to Midamor, any other medications, or any of the ingredients in Midamor. Ask your pharmacist for a list of the ingredients.
  • Tell your doctor if you are taking spironolactone (Aldactone, in Aldactazide), other triamterene-containing medications, or potassium supplements, or potassium-containing drug supplements. Your doctor will probably tell you not to take Midamor if you are taking one or more of these medications.
  • Tell your doctor and pharmacist what other prescription and over-the-counter medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: angiotensin converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril (Capoten), fosinopril, lisinopril (in Prinzide, in Zestoretic), moexipril (Univasc, in Uniretic) , perindopril (Aceon), quinapril (Accupril, in Accuretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); angiotensin II receptor antagonists (ARBs) such as azilsartan (Edarbi, Edarbyclor), candesartan (Atacand, in Atacand HCT), eprosartan (Teveten, in Teveten HCT), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar) olmesartan (Benicar, in Azor, Benicar HCT), telmisartan (Micardis, in Micardis HCT) and valsartan (Diovan, in Diovan HCT, Exforge); cyclosporine (Gengraf, Neoral, Sandimmune); lithium (Lithobid); o nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others), indomethacin (Indocin), and naproxen (Aleve, Naprosyn, others); or tacrolimus (Astagraf XL, Prograf). Your doctor may need to change the doses of your medications or monitor you closely for side effects.
  • Tell your doctor if you have kidney disease. Your doctor may tell you not to take Midamor.
  • Tell your doctor if you have or have ever had diabetes or liver disease.
  • Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking Midamor, call your doctor immediately.

What special dietary instructions should I follow?

Avoid salt substitutes that contain potassium while you are taking this medicine. Talk to your doctor about the amount of potassium-rich foods (for example, bananas, prunes, raisins, and orange juice) that you can have in your diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for the one you forgot.

What side effects can this medication cause?

Midamor may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • headache
  • heartburn
  • loss of appetite
  • nausea
  • diarrhea
  • vomiting
  • gas

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

  • dry mouth; thirst; numbness and tingling; confusion; muscle weakness, stomach pain, or cramps; fast heartbeat and other signs of dehydration and electrolyte imbalance
  • yellowing of the skin or eyes
  • chest pain
  • rash
  • itching
  • hives
  • difficulty breathing or swallowing

Midamor may cause other side effects. Call your doctor if you have any unusual problems while taking this medicine.

If you experience a serious side effect, you or your doctor can submit a report online to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medicine in the container it came in, tightly closed, and out of the reach of children. Store at room temperature and away from excess heat and moisture (not in the bathroom). Do not freeze.

Unnecessary medications must be disposed of in special ways to ensure they cannot be consumed by pets, children, and others. However, you should not flush this medicine down the toilet. Instead, the best way to dispose of your medications is through a drug take-back program. Talk to your pharmacist or contact your local garbage / recycling department to find out about take-back programs in your community. See the FDA Safe Drug Disposal website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medicines out of the sight and reach of children, since many containers (such as those containing weekly pills and those for eye drops, creams, patches and inhalers) are not resistant to children and small children can easily open them. To protect young children from poisoning, always close the safety caps and immediately place the medicine in a safe place, one that is upright and out of their sight and reach. http://www.upandaway.org

In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim collapsed, had a seizure, is having trouble breathing, or is unable to wake up, immediately call 911 for emergency services.

What other information should I know?

Keep all appointments with your doctor and the laboratory. You should monitor your blood pressure regularly to determine your response to Midamor. Your doctor may order certain lab tests to check your body’s response to Midamor.

Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription.

It is important that you keep a written list of all prescription and over-the-counter (over-the-counter) medications you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should take this list with you each time you visit a doctor or if you go into hospital. It is also important information to take with you in case of emergencies.

Brand Names

  • Midamor®

Disclaimer: We have made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

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