Carospir : Uses, Side Effects, Interactions & More

IMPORTANT WARNING:

Carospir has caused tumors in laboratory animals. Talk to your doctor about the risks and benefits of using this medication for your condition.

Why is this medication prescribed?

Carospir (Spironolactone) is used to treat certain patients with hyperaldosteronism (the body makes too much aldosterone, a natural hormone); low potassium levels; heart failure; and in patients with edema (fluid retention) caused by various conditions, including liver or kidney disease. It is also used alone or with other medications to treat high blood pressure. Carospir is in a class of medications called aldosterone receptor antagonists. It causes the kidneys to remove unnecessary water and sodium from the body into the urine, but reduces the loss of potassium from the body.

High blood pressure is a common condition and, when left untreated, it can cause damage to the brain, heart, blood vessels, kidneys, and other parts of the body. Damage to these organs can cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medications, making lifestyle changes will also help control your blood pressure. These changes include eating a diet low in fat and salt, maintaining a healthy weight, exercising for at least 30 minutes most days, not smoking, and consuming alcohol in moderation.

How should this medicine be used?

Carospir (Spironolactone) comes as a tablet and a suspension (liquid; Carospir) to take by mouth. It is usually taken once or twice a day. Take Carospir suspension constantly, either with food or without food each time. Take Carospir at around the same time every day. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any parts you do not understand. Take Carospir exactly as directed. Do not take more or less, or take it more often than prescribed by your doctor.

Shake the oral suspension well before each use to mix the medicine evenly.

Your doctor may start with a low dose of Carospir and gradually increase your dose.

Carospir tablets and suspension release the medicine differently in your body and cannot be substituted for each other. Only take the Carospir product prescribed by your doctor and do not switch to a different Carospir product unless your doctor tells you to.

Carospir controls high blood pressure, edema, heart failure, and hyperaldosteronism, but it does not cure these conditions. It may take 2 weeks or longer for Carospir to take full effect. Keep taking Carospir even if you feel fine. Do not stop taking Carospir without consulting your doctor.

Other uses for this medicine

Carospir is also used in combination with other medications to treat precocious puberty (a condition that causes boys to enter puberty too early, resulting in the development of sexual characteristics in girls generally under the age of 8 and in boys generally under 9 years). ) or myasthenia gravis (MG, a disease in which nerves do not function properly and patients may experience weakness, numbness, loss of muscle coordination, and problems with vision, speech, and bladder control). Carospir can also be used to treat certain patients with abnormal facial hair. Talk to your doctor about the possible risks of using this drug for your condition.

This medicine is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking Carospir,

  • Tell your doctor and pharmacist if you are allergic to Carospir; any other medication; or any of the ingredients in Carospir tablets. Ask your pharmacist for a list of the ingredients.
  • Tell your doctor if you are taking eplerenone (Inspra). Your doctor may tell you not to take Carospir if you are taking this medicine.
  • Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: aminoglycoside antibiotics such as amikacin, gentamicin, kanamycin, neomycin (Neo-Rx, Neo-Fradin), streptomycin, and tobramycin (Tobi); angiotensin converting enzyme (ACE) inhibitors, such as benazepril (Lotensin, in Lotrel), captopril (Capoten), enalapril (Vasotec), fosinopril, lisinopril (in Prinzide, in Zestoretic), moexipril (Univasc, in Uniretic), perindopril , (Aceon), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace) and trandolapril (Mavik, in Tarka); angiotensin II antagonists (angiotensin receptor blockers; ARBs) such as azilsartan (Edarbi, Edarbyclor), candesartan (Atacand, in Atacand HCT), eprosartan (Teveten, in Teveten HCT), irbesartan (Avapro, in Avalide), losartan (Cozaar Hyzaar), olmesartan (Benicar, in Azor, Benicar HCT, Tribenzor), telmisartan (Micardis, in Micardis HCT) and valsartan (Diovan, in Diovan HCT, Exforge); aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin), indomethacin (Indocin, Tivorbex), and naproxen (Aleve, Naprosyn); barbiturates such as phenobarbital; cholestyramine (Prevalite); cisplatin; digoxin (Lanoxin); diuretics (‘water pills’) including potassium-sparing diuretics such as amiloride (Midamor) and triamterene (Dyrenium, in Dyazide, in Maxzide); heparin or low molecular weight heparin enoxaparin (Lovenox); lithium (Lithobid); medications to treat high blood pressure; narcotic pain medication; oral steroids such as dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos); potassium supplements; and trimethoprim (Primsol, ex Bactrim).
  • Tell your doctor if you have Addison’s disease or other conditions that can cause high blood potassium levels or kidney disease. Your doctor may tell you not to take Carospir.
  • Tell your doctor if you have liver disease.
  • Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking Carospir, call your doctor.
  • If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking Carospir.
  • You should know that drinking alcohol with this medicine can cause dizziness, lightheadedness, and fainting when you get up too quickly from lying down. Talk to your doctor about drinking alcohol while taking Carospir.

What special dietary instructions should I follow?

Follow your doctor’s instructions for your meals, including tips for a low-salt (sodium) diet and a daily exercise program. Avoid salt substitutes that contain potassium while you are taking this medicine. Talk to your doctor about the amount of potassium-rich foods (for example, bananas, prunes, raisins, and orange juice) to have in your diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for the one you forgot.

What side effects can this medication cause?

Carospir may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • vomiting
  • diarrhea
  • stomach pain or cramps
  • enlarged or painful breasts in men or women
  • irregular menstrual periods
  • vaginal bleeding in post-menopausal (‘after the change of life’, the end of monthly menstrual periods) women
  • difficulty maintaining or achieving an erection
  • deepening of voice
  • increased hair growth on parts of the body
  • drowsiness
  • tiredness
  • restlessness

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

  • muscle weakness, pain, or cramps
  • pain, burning, numbness, or tingling in the hands or feet
  • inability to move arms or legs
  • changes in heartbeat
  • confusion
  • nausea
  • extreme tiredness
  • dry mouth, thirst, dizziness, unsteadiness, headache, or other signs of dehydration
  • unusual bleeding or bruising
  • lack of energy
  • loss of appetite
  • pain in the upper right part of the stomach
  • yellowing of the skin or eyes
  • flu-like symptoms
  • rash
  • hives
  • itching
  • difficulty breathing or swallowing
  • vomiting blood
  • blood in stools
  • decreased urination
  • fainting

If you experience a serious side effect, you or your doctor can submit a report online to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medicine in the container it came in, tightly closed, and out of the reach of children. Store at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medicines out of the sight and reach of children, since many containers (such as those containing weekly pills and those for eye drops, creams, patches and inhalers) are not resistant to children and small children can easily open them. To protect young children from poisoning, always close the safety caps and immediately place the medicine in a safe place, one that is upright and out of their sight and reach. http://www.upandaway.org

Unnecessary medications must be disposed of in special ways to ensure that pets, children, and others cannot consume them. However, you should not flush this medicine down the toilet. Instead, the best way to dispose of your medications is through a drug take-back program. Talk to your pharmacist or contact your local garbage / recycling department to find out about take-back programs in your community. See the FDA Safe Drug Disposal website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim collapsed, had a seizure, is having trouble breathing, or is unable to wake up, immediately call 911 for emergency services.

Symptoms of overdose may include the following:

  • drowsiness
  • confusion
  • rash
  • nausea
  • vomiting
  • dizziness
  • diarrhea
  • tingling in arms and legs
  • loss of muscle tone
  • weakness or heaviness in legs
  • irregular or slow heartbeat

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain laboratory tests to check your body’s response to Carospir.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking Carospir.

Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription.

It is important that you keep a written list of all prescription and over-the-counter (over-the-counter) medications you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should take this list with you each time you visit a doctor or if you go into hospital. It is also important information to take with you in case of emergencies.

Brand Names

  • Aldactone®
  • Carospir®

Disclaimer: We have made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

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