Amlexanox : Uses, Side Effects, Interactions & More


Amlexanox is no longer available in the US. If you are currently using amlexanox, you should call your doctor to discuss switching to another treatment.

Why is this medication prescribed?

Amlexanox is used to treat mouth ulcers called aphthous ulcers or canker sores. Decrease the time it takes for ulcers to heal. As amlexanox reduces your healing time, it also decreases the pain you feel.

This medicine is sometimes prescribed for other uses; ask your doctor, dentist or pharmacist for more information.

How should this medicine be used?

Amlexanox comes as a beige paste. Amlexanox should be used as soon as possible after you notice the symptoms of an ulcer. Amlexanox is generally applied four times a day, after brushing and flossing after breakfast, lunch, dinner, and before bed. Squeeze 1/4 inch (0.6 centimeter) of the paste onto your finger. With gentle pressure, apply amlexanox to each mouth ulcer. Wash your hands immediately after using amlexanox. Amlexanox is only used until the ulcer has healed, usually within 10 days. Contact your doctor or dentist if no significant healing has occurred within 10 days.

Follow the directions on your prescription label carefully, and ask your doctor, dentist, or pharmacist to explain any parts you don’t understand. Use amlexanox exactly as directed. Do not use more or less or use it more often than prescribed by your doctor or dentist.

What special precautions should I follow?

Before using amlexanox,

  • Tell your doctor or dentist and pharmacist if you are allergic to amlexanox or any other medications.
  • Tell your doctor and pharmacist what prescription and nonprescription medications you are taking, including vitamins and herbal products.
  • Tell your doctor or dentist if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using amlexanox, call your doctor or dentist.

What should I do if I forget a dose?

Apply the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for the one you forgot.

What side effects can this medication cause?

Amlexanox may cause side effects. Tell your doctor or dentist if any of these symptoms are severe or do not go away:

  • slight pain, stinging, or burning of the skin that comes and goes
  • nausea
  • diarrhea

If you experience the following symptom, call your doctor or dentist immediately:

  • rash

If you experience a serious side effect, you or your doctor can submit a report online to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program ( or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medicine in the container it came in, tightly closed, and out of the reach of children. Store at room temperature and away from excess heat and moisture (not in the bathroom).

Unnecessary medications must be disposed of in special ways to ensure that pets, children, and others cannot consume them. However, you should not flush this medicine down the toilet. Instead, the best way to dispose of your medications is through a drug take-back program. Talk to your pharmacist or contact your local garbage / recycling department to find out about take-back programs in your community. See the FDA Safe Drug Disposal website ( for more information if you do not have access to a take-back program.

It is important to keep all medicines out of the sight and reach of children, since many containers (such as those containing weekly pills and those for eye drops, creams, patches and inhalers) are not resistant to children and small children can easily open them. To protect young children from poisoning, always close the safety caps and immediately place the medicine in a safe place, one that is upright and out of their sight and reach.

What other information should I know?

Keep all appointments with your doctor or dentist. Amlexanox is for external use only. Do not get amlexanox in your eyes. If it gets into your eyes, rinse them immediately.

Don’t let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription. Tell your doctor or dentist if your ulcers get worse or do not improve within 10 days.

It is important that you keep a written list of all prescription and over-the-counter (over-the-counter) medications you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should take this list with you each time you visit a doctor or if you go into hospital. It is also important information to take with you in case of emergencies.

Brand Names

  • Aphthasol®

Disclaimer: We have made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

Leave a Reply

Your email address will not be published. Required fields are marked *