Alfuzosin : Uses, Side Effects, Interactions & More

Why is this medication prescribed?

Alfuzosin is used in men to treat symptoms of an enlarged prostate (benign prostatic hyperplasia or BPH), including difficulty urinating (hesitation, dribbling, weak flow, and incomplete bladder emptying), painful urination, and frequency and urgency. urinary. Alfuzosin is in a class of medications called alpha blockers. It works by relaxing the muscles of the prostate and bladder to allow urine to flow more easily.

How should this medicine be used?

Alfuzosin comes as an extended-release (long-acting) tablet to take by mouth. It is usually taken once a day, immediately after a meal. Do not take alfuzosin on an empty stomach. To remind you to take alfuzosin, take it after the same meal every day. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any parts you do not understand. Take alfuzosin exactly as directed. Do not take more or less, or take it more often than prescribed by your doctor.

Swallow the tablets whole; do not split, chew, or crush them.

Alfuzosin controls BPH but does not cure it. Keep taking alfuzosin even if you feel fine. Do not stop taking alfuzosin without consulting your doctor.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking alfuzosin,

  • Tell your doctor and pharmacist if you are allergic to alfuzosin, any other medications, or any of the ingredients in alfuzosin. Ask your pharmacist for a list of the ingredients.
  • Tell your doctor if you are taking itraconazole (Sporanox), ketoconazole (Nizoral), or ritonavir (Norvir, in Kaletra). Your doctor will likely tell you not to take alfuzosin.
  • Tell your doctor if you have liver disease. Your doctor may tell you not to take alfuzosin.
  • Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amiodarone (Cordarone); aprepitant (Emend); Atenolol (Tenormin); cimetidine (Tagamet); cisapride (not available in the US); claritormycin (Biaxin, in Prevpac); cyclosporine (Neoral, Sandimmune); danazol (Danocrine); Delavirdine (Rescriptor); diltiazem (Cardizem, Dilacor, Tiazac, others); disopyramide (Norpace), dofetilide (Tikosyn); efavirenz (Sustiva); erythromycin (E.E.S., E-Mycin, Erythrocin), fluconazole (Diflucan); fluoxetine (Prozac, Sarafem); fluvoxamine (Luvox); HIV protease inhibitors such as atazanavir (Reyataz), indinavir (Crixivan), lopinavir (in Kaletra), nelfinavir (Viracept), and saquinavir (Fortovase, Invirase); hormonal contraceptives (contraceptive pills, rings and patches); isoniazid (INH, Nydrazid); lovastatin (Adivicor, Altocor, Mevacor); medications for high blood pressure; erectile dysfunction (ED) medications such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra); metronidazole (Flagyl); moxifloxacin (Avelox); nefazodone; other alpha blockers such as doxazosin (Cardura), prazosin (Minipress), terazosin (Hytrin), and tamsulosin (Flomax); pimozide (Orap); procainamide (Procanbid, Pronestyl); quinidine (Quinidex); sertraline (Zoloft); sotalol (Betapace,); sparfloxacin (Zagam); thioridazine (Mellaril); troleandomycin (TAO); Verapamil (Calan, Covera, Isoptin, Verelan); and zafirlukast (Accolate). Your doctor may need to change the doses of your medications or monitor you closely for side effects.
  • Tell your doctor if you or anyone in your family has an irregular heartbeat; or if you have or have ever had prostate cancer; angina (chest pain); low blood pressure; or heart or kidney disease; and if you’ve ever been dizzy, fainted, or had low blood pressure after taking any medicine.
  • You should know that alfuzosin is only used in men. Women should not take alfuzosin, especially if they are or could become pregnant or are breastfeeding. If a pregnant woman takes alfuzosin, she should call her doctor.
  • If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking alfuzosin. If you need to have eye surgery at any time during or after your treatment, be sure to tell your doctor that you are taking or have taken alfuzosin.
  • You should know that alfuzosin can cause dizziness, lightheadedness, and fainting, especially when you get up too quickly after lying down. This is more common when you start taking alfuzosin. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up. If these symptoms do not improve, call your doctor. Avoid driving, operating machinery, or performing dangerous tasks until you know how this drug affects you.

What special dietary instructions should I follow?

Talk to your doctor about eating grapefruit or drinking grapefruit juice while taking this medication.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for the one you forgot.

What side effects can this medication cause?

Alfuzosin may cause side effects. Tell your doctor if any of these symptoms or those listed in the SPECIAL PRECAUTIONS section are severe or do not go away:

  • tiredness
  • headache
  • runny or stuffy nose
  • pain
  • stomach pain
  • heartburn
  • constipation
  • nausea
  • decrease in sexual ability
  • sore throat, fever, chills, cough and other signs of infection

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

  • rash
  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • hoarseness
  • difficulty swallowing or breathing
  • chest pain
  • fainting

Alfuzosin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

What should I know about storage and disposal of this medication?

Keep this medicine in the container it came in, tightly closed, and out of the reach of children. Store at room temperature and away from light and excess heat and humidity (not in the bathroom).

Unnecessary medications must be disposed of in special ways to ensure that pets, children, and others cannot consume them. However, you should not flush this medicine down the toilet. Instead, the best way to dispose of your medications is through a drug take-back program. Talk to your pharmacist or contact your local garbage / recycling department to find out about take-back programs in your community. See the FDA Safe Drug Disposal website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medicines out of the sight and reach of children, as many containers (such as those containing weekly pills and those for eye drops, creams, patches, and inhalers) are not child-resistant and small children can easily open them. To protect young children from poisoning, always close the safety caps and immediately place the medicine in a safe place, one that is upright and out of their sight and reach. http://www.upandaway.org

In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim collapsed, had a seizure, is having trouble breathing, or is unable to wake up, immediately call 911 for emergency services.

Symptoms of overdose may include:

  • dizziness
  • fainting
  • lightheadedness
  • blurred vision
  • nausea

What other information should I know?

Keep all your appointments with your doctor.

Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription.

It is important that you keep a written list of all prescription and over-the-counter (over-the-counter) medications you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should take this list with you each time you visit a doctor or if you go into hospital. It is also important information to take with you in case of emergencies.

Brand Names

  • Uroxatral®

Disclaimer: We have made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.  

   

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