Albiglutide Injection : Uses, Side Effects, Interactions & More


Albiglutide injection may increase the risk of developing thyroid gland tumors, including medullary thyroid carcinoma (MTC; a type of thyroid cancer). Laboratory animals that received drugs similar to albiglutide developed tumors, but it is not known whether these drugs increase the risk of tumors in humans. Tell your doctor if you or any member of your family have or have ever had TCM or multiple endocrine neoplasia syndrome type 2 (MEN 2; condition that causes tumors in more than one gland in the body). If so, your doctor will probably tell you not to use albiglutide injection. If you experience any of the following symptoms, call your doctor immediately: a lump or swelling in the neck; hoarseness; difficulty swallowing or difficulty breathing.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain tests to check your body’s response to albiglutide injection.

Your doctor or pharmacist will give you the manufacturer’s patient information sheet (Medication Guide) when you start treatment with albiglutide injection and each time you get a refill. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website ( or the manufacturer’s website to obtain the Medication Guide.

Talk to your doctor about the risks of using albiglutide injection.

Why is this medication prescribed?

Albiglutide injection is used with a diet and exercise program to control blood sugar levels in adults with type 2 diabetes (a condition in which the body does not use insulin normally and therefore cannot control the amount of insulin). blood sugar) when other medicines do not control levels well enough. Albiglutide injection is not used to treat type 1 diabetes (a condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that can develop if hyperglycemia is not treated). . Albiglutide injection is in a class of medications called incretin mimetics. It works by helping the pancreas to release the correct amount of insulin when blood sugar levels are high. Insulin helps move sugar from the blood to other body tissues where it is used for energy. Albiglutide injection also works by slowing the movement of food through the stomach.

Over time, people with diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Using medicine, making lifestyle changes (for example, diet, exercise, quitting smoking), and regularly checking your blood sugar can help control your diabetes and improve your health. This therapy can also lower your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numbness, cold legs or feet; decreased sexual ability in men and women) , eye problems, including changes. or vision loss or gum disease. Your doctor and other healthcare providers will talk with you about the best way to control your diabetes.

How should this medicine be used?

Albiglutide injection comes as a powder that is mixed with water in a pre-filled dosing pen to inject subcutaneously (under the skin). It is usually injected once a week regardless of meals. Use albiglutide injection on the same day each week at any time of the day. You can change the day of the week you use albiglutide as long as 4 or more days have passed since you used your last dose. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any parts you do not understand. Use albiglutide injection exactly as directed. Do not use more or less or use it more often than prescribed by your doctor.

Albiglutide injection controls diabetes but does not cure it. Keep using albiglutide injection even if you feel fine. Do not stop using albiglutide injection without consulting your doctor.

Albiglutide comes in pre-filled dosing pens that contain enough medicine for one dose. Always inject albiglutide into your own pre-filled dosing pen; never mix it with any other medicine.

Carefully read the manufacturer’s instructions for use that come with the medicine. These instructions describe how to prepare and inject an injection dose of albiglutide. Be sure to ask your pharmacist or doctor if you have any questions about how to prepare or inject this medicine.

Always look at your albiglutide before you inject. It should be transparent, yellow and free of solid particles.

You can inject your albiglutide into the upper arm, thigh, or stomach area. Never inject albiglutide into a vein or muscle. Change (rotate) the injection site within the chosen area with each dose. You can inject albiglutide and insulin in the same area of ​​the body, but you should not give the injections side by side.

Never reuse or share needles or pens. Always use a new needle for each injection. Dispose of needles in a puncture resistant container. Ask your doctor or pharmacist how to dispose of the puncture resistant container.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before using albiglutide injection,

  • Tell your doctor and pharmacist if you are allergic to albiglutide, any other medications, or any of the ingredients in albiglutide injection. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
  • Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. It is especially important to tell your doctor about all the medications you take by mouth because albiglutide may change the way your body absorbs these medications. Also be sure to mention insulin or oral medications for diabetes especially sulfonylureas, including chlorpropamide (Diabinese), glimepiride (Amaryl, in Avandaryl, in Duetact), glipizide (Glucotrol), glyburide (DiaBeta, Glynase, in Glucovance), tolazamide, and tolbutamide. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • Tell your doctor if you have or have ever had pancreatitis (inflammation of the pancreas); severe stomach problems, including gastroparesis (slowed movement of food from the stomach to the small intestine) or problems digesting food; or kidney or liver disease.
  • Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using albiglutide injection, call your doctor.
  • Ask your doctor what to do if you get sick, develop an infection or fever, or experience unusual stress. These conditions can affect your blood sugar and the amount of albiglutide you may need.

What special dietary instructions should I follow?

Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian.

What should I do if I forget a dose?

Use the missed dose as soon as you remember. However, if it has been more than 3 days after the missed dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for the one you forgot.

What side effects can this medication cause?

This medication may cause changes in your blood sugar. You should know the symptoms of low and high blood sugar and what to do if you have these symptoms.

Albiglutide injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • diarrhea
  • nausea
  • heartburn
  • redness, swelling, or itching at the site of the injection
  • cough or flu-like symptoms

Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, stop using albiglutide injection and call your doctor immediately or get emergency medical treatment:

  • ongoing pain that begins in the upper left or middle of the stomach but may spread to the back
  • vomiting
  • hives
  • rash
  • itching
  • difficulty breathing

Albiglutide injection may cause other side effects. Call your doctor if you have any unusual problems while using this medicine.

If you experience a serious side effect, you or your doctor can submit a report online to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program ( or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medicine in the container it came in, tightly closed, and out of the reach of children. Store at room temperature for up to 4 weeks before use or in the refrigerator, and away from excess heat and moisture (not in the bathroom). Do not freeze.

Unnecessary medications must be disposed of in special ways to ensure they cannot be consumed by pets, children, and others. However, you should not flush this medicine down the toilet. Instead, the best way to dispose of your medications is through a drug take-back program. Talk to your pharmacist or contact your local garbage / recycling department to find out about take-back programs in your community. See the FDA Safe Drug Disposal website ( for more information if you do not have access to a take-back program.

It is important to keep all medicines out of the sight and reach of children, since many containers (such as those containing weekly pills and those for eye drops, creams, patches and inhalers) are not resistant to children and small children can easily open them. To protect young children from poisoning, always close the safety caps and immediately place the medicine in a safe place, one that is upright and out of their sight and reach.

In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at If the victim collapsed, had a seizure, is having trouble breathing, or is unable to wake up, immediately call 911 for emergency services.

Symptoms of overdose may include:

  • severe nausea and vomiting

What other information should I know?

Don’t let anyone use your medicine. Ask your pharmacist any questions you have about refilling your prescription.

It is important that you keep a written list of all prescription and over-the-counter (over-the-counter) medications you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should take this list with you each time you visit a doctor or if you go into hospital. It is also important information to take with you in case of emergencies.

Brand Names

  • Tanzeum®

Disclaimer: We have made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

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