Addyi : Uses, Side Effects, Interactions & More

Addyi can cause very low blood pressure, causing dizziness, lightheadedness, and fainting. Tell your doctor if you have or have ever had liver disease or if you drink or have ever drunk large amounts of alcohol. Drinking alcohol at about the same time as taking Addyi can increase your risk of having very low blood pressure. Wait at least 2 hours after drinking 1 or 2 alcoholic beverages before taking Addyi before bed. If you drink 3 or more alcoholic beverages at night, skip your dose of Addyi that night. After taking Addyi at bedtime, do not drink alcohol until the next day. Your doctor will probably tell you not to take Addyi. Tell your doctor and pharmacist if you are taking any of the following medications or have taken them in the past 2 weeks: amprenavir (Agenerase; no longer available in the US), Atazanavir (Reyataz, in Evotaz), boceprevir ( Victrelis), ciprofloxacin (Cipro), clarithromycin (Biaxin, in Prevpac), conivaptan (Vaprisol), diltiazem (Cartia XT, Diltzac, Tiazac, others), erythromycin (EES, Erytab, Erythrocin), fluconazole (Diflucan) ) Crixivan), itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), nefazodone, nelfinavir (Viracept), posaconazole (Noxafil), ritonavir (Norvir, in Kaletra, in Viekira Pak), saquinavir (Invirase), telaprevir (Incivek; ya not available in the USA), telithromycin (Ketek) and verapamil (Calan, Covera, Verelan, in Tarka). Your doctor may tell you not to take Addyi, change your medications during your treatment with Addyi, or monitor it carefully for side effects. Do not eat grapefruit or drink grapefruit juice while taking Addyi. If you have any of the following symptoms, call your doctor immediately and lie down: dizziness, fainting, or dizziness.

Keep all your appointments with your doctor.

Your doctor or pharmacist will provide you with the manufacturer’s patient information sheet (Medication Guide) when you start treatment with Addyi and each time you get a refill. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website ( or the manufacturer’s website to obtain the Medication Guide.

Why is this medication prescribed?
Addyi (Flibanserin) is used to treat women with hypoactive sexual desire disorder (HSDD; a low sexual desire that causes distress or interpersonal difficulty) who have not experienced menopause (life change; the end of monthly menstrual periods). Addyi should not be used to treat HSDD in women who have gone through menopause or in men or to improve sexual performance. Addyi belongs to a class of medications called a serotonin 1A receptor agonist / serotonin 2A receptor antagonist. It works by changing the activity of serotonin and other natural substances in the brain.

How should this medicine be used?
Addyi (Flibanserin) comes as a tablet to take by mouth. It is usually taken once a day at bedtime. Take Addyi at bedtime every day. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any part you do not understand. Take Addyi exactly as directed. Do not take more or less or take it more often than prescribed by your doctor.

If your symptoms do not improve after 8 weeks of treatment, call your doctor.

Other uses for this Medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking Addyi,

  • Tell your doctor and pharmacist if you are allergic to Addyi, any other medications, or any of the ingredients in Addyi tablets. Consult your pharmacist or consult the Medication Guide for a list of ingredients.
  • Tell your doctor and pharmacist what other prescription and over-the-counter medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: antidepressants such as fluoxetine (Prozac, Sarafem); cimetidine antifungals (Tagamet); digoxin (Lanoxin); diphenhydramine (Benadryl); medications for anxiety or mental illness; seizure medications such as carbamazepine (Epitol, Tegretol, Teril, others), phenobarbital, and phenytoin (Dilantin, Phenytek); opioid (narcotic) medications for pain control; oral contraceptives; proton pump inhibitors including dexlansoprazole (Dexilant), esomeprazole (Nexium, Vimovo), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix) or rabeprazole (Aciphex); ranitidine (Zantac); rifabutin (mycobutin); rifampicin (Rifadin, Rimactane, in Rifamate, in Rifater); sedatives sirolimus (Rapamune); sleeping pills; and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • Tell your doctor what herbal products you are taking, especially ginkgo, resveratrol, and St. John’s wort.
  • Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Addyi, call your doctor. Do not breastfeed while taking Addyi.
  • You should know that Addyi can cause drowsiness. Do not drive a car or operate machinery until at least 6 hours after your Addyi dose and until you know how this medication affects you.

What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?
If a dose is missed at bedtime, take the next dose at bedtime the following day. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Addyi may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea
  • tiredness
  • difficulty falling asleep or staying asleep
  • dry mouth
  • constipation

Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING and SPECIAL PRECAUTIONS sections, call your doctor immediately:

  • excessive sleepiness

Addyi may cause other side effects. Call your doctor if you have any unusual problems while taking this medicine.

If you experience a serious side effect, you or your doctor can submit an online report to the Food and Drug Administration (FDA) MedWatch Adverse Event Reporting Program ( or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?
Keep this medicine in its container, tightly closed and out of the reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medications out of the sight and reach of children, as many containers (such as those for taking pills weekly and those used for eye drops, creams, patches, and inhalers) are not resistant to children and children. young children can easily open them. To protect young children from poisoning, always close the safety caps and immediately put the medicine in a safe place, one that is up and away and out of your sight and reach.

Unnecessary medications must be disposed of in a special way to ensure that pets, children and others cannot consume them. However, you should not flush this medicine down the toilet. Instead, the best way to get rid of your medication is through a medication take-back program. Talk to your pharmacist or contact your local recycling / garbage department to find out about return programs in your community. Consult the FDA’s Safe Drug Disposal website ( for more information if you do not have access to a take-back program.

In case of emergency/overdose
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at If the victim collapsed, had a seizure, is having trouble breathing, or cannot wake up, call 911 immediately.

What other information should I know?
Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription.

It is important to keep a written list of all prescription and over-the-counter (non-prescription) medications you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should carry this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names

  • Addyi

Disclaimer: We have made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

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